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Predicting Cross-Reactivity and Antigen Specificity of T Cell Receptors

Adaptive immune recognition is mediated by specific interactions between heterodimeric T cell receptors (TCRs) and their cognate peptide-MHC (pMHC) ligands, and the methods to accurately predict TCR:pMHC interaction would have profound clinical, therapeutic and pharmaceutical applications. Herein, w...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lee, Chloe H., Salio, Mariolina, Napolitani, Giorgio, Ogg, Graham, Simmons, Alison, Koohy, Hashem
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642207/
https://ncbi.nlm.nih.gov/pubmed/33193332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.565096
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