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Coarse-grained modelling of DNA plectoneme pinning in the presence of base-pair mismatches

Damaged or mismatched DNA bases result in the formation of physical defects in double-stranded DNA. In vivo, defects in DNA must be rapidly and efficiently repaired to maintain cellular function and integrity. Defects can also alter the mechanical response of DNA to bending and twisting constraints,...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Desai, Parth Rakesh, Brahmachari, Sumitabha, Marko, John F, Das, Siddhartha, Neuman, Keir C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641772/
https://ncbi.nlm.nih.gov/pubmed/33045724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa836
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