A Vaccine Based on Kunitz-Type Molecule Confers Protection Against Fasciola hepatica Challenge by Inducing IFN-γ and Antibody Immune Responses Through IL-17A Production

Fasciola hepatica is helminth parasite found around the world that causes fasciolosis, a chronic disease affecting mainly cattle, sheep, and occasionally humans. Triclabendazole is the drug of choice to treat this parasite. However, the continuous use of this drug has led to the development of paras...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Silvane, Leonardo, Celias, Daiana Pamela, Romagnoli, Pablo Alberto, Maletto, Belkys Angélica, Sanchez Vallecillo, María Fernanda, Chiapello, Laura Silvina, Palma, Santiago Daniel, Allemandi, Daniel Alberto, Sanabria, Rodrigo Eduardo Fabrizio, Pruzzo, César Iván, Motrán, Claudia Cristina, Cervi, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641617/
https://ncbi.nlm.nih.gov/pubmed/33193292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.02087
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