Getting DNA and RNA out of the dark with 2CNqA: a bright adenine analogue and interbase FRET donor

With the central role of nucleic acids there is a need for development of fluorophores that facilitate the visualization of processes involving nucleic acids without perturbing their natural properties and behaviour. Here, we incorporate a new analogue of adenine, 2CNqA, into both DNA and RNA, and e...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Wypijewska del Nogal, Anna, Füchtbauer, Anders F, Bood, Mattias, Nilsson, Jesper R, Wranne, Moa S, Sarangamath, Sangamesh, Pfeiffer, Pauline, Rajan, Vinoth Sundar, El-Sagheer, Afaf H, Dahlén, Anders, Brown, Tom, Grøtli, Morten, Wilhelmsson, L Marcus
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Chemical Biology and Nucleic Acid Chemistry
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641321/
https://ncbi.nlm.nih.gov/pubmed/32558908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa525
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