Broad genic repression domains signify enhanced silencing of oncogenes

Cancers result from a set of genetic and epigenetic alterations. Most known oncogenes were identified by gain-of-function mutations in cancer, yet little is known about their epigenetic features. Through integrative analysis of 11,596 epigenomic profiles and mutations from >8200 tumor-normal pair...

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Publicado no:Nat Commun
Main Authors: Zhao, Dongyu, Zhang, Lili, Zhang, Min, Xia, Bo, Lv, Jie, Gao, Xinlei, Wang, Guangyu, Meng, Qingshu, Yi, Yang, Zhu, Sen, Tomoiaga, Alin S., Lee, Min Gyu, Cooke, John P., Cao, Qi, Chen, Kaifu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641226/
https://ncbi.nlm.nih.gov/pubmed/33144558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18913-8
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