Circadian rhythm influences induction of trained immunity by BCG vaccination

BACKGROUND: The antituberculosis vaccine bacillus Calmette-Guérin (BCG) reduces overall infant mortality. Induction of innate immune memory, also termed trained immunity, contributes toward protection against heterologous infections. Since immune cells display oscillations in numbers and function th...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: de Bree, L. Charlotte J., Mourits, Vera P., Koeken, Valerie A.C.M., Moorlag, Simone J.C.F.M., Janssen, Robine, Folkman, Lukas, Barreca, Daniele, Krausgruber, Thomas, Fife-Gernedl, Victoria, Novakovic, Boris, Arts, Rob J.W., Dijkstra, Helga, Lemmers, Heidi, Bock, Christoph, Joosten, Leo A.B., van Crevel, Reinout, Benn, Christine S., Netea, Mihai G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641012/
https://ncbi.nlm.nih.gov/pubmed/32692732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133934
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