Circadian rhythm influences induction of trained immunity by BCG vaccination

BACKGROUND: The antituberculosis vaccine bacillus Calmette-Guérin (BCG) reduces overall infant mortality. Induction of innate immune memory, also termed trained immunity, contributes toward protection against heterologous infections. Since immune cells display oscillations in numbers and function th...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: de Bree, L. Charlotte J., Mourits, Vera P., Koeken, Valerie A.C.M., Moorlag, Simone J.C.F.M., Janssen, Robine, Folkman, Lukas, Barreca, Daniele, Krausgruber, Thomas, Fife-Gernedl, Victoria, Novakovic, Boris, Arts, Rob J.W., Dijkstra, Helga, Lemmers, Heidi, Bock, Christoph, Joosten, Leo A.B., van Crevel, Reinout, Benn, Christine S., Netea, Mihai G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
Teme:
Clinical Medicine
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641012/
https://ncbi.nlm.nih.gov/pubmed/32692732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133934
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