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The intervention of valproic acid on the tumorigenesis induced by an environmental carcinogen of PAHs

This study investigated whether valproic acid (VPA, a histone deacetylase inhibitor) can interfere with the carcinogenicity of polycyclic aromatic hydrocarbons (PAHs). A typical representative compound of PAHs, 7,12-Dimethylbenz[a]anthracene (DMBA), was used to induce rat breast cancer. The results...

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Detalhes bibliográficos
Publicado no:Toxicol Res (Camb)
Main Authors: Peng, Junxuan, Cai, Zuchao, Zhao, Ruixue, Chen, Jiahao, Liu, Guochao, Dong, Chao, Lim, David, Feng, Zhihui
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7640934/
https://ncbi.nlm.nih.gov/pubmed/33178421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxres/tfaa069
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