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Indole-3-carbinol regulates microglia homeostasis and protects the retina from degeneration

BACKGROUND: Retinal degenerative diseases significantly contribute to visual impairment and blindness. Microglia reactivity is a hallmark of neurodegenerative diseases including retinal cell death and immunomodulation emerges as a therapeutic option. Indole-3-carbinol (I3C) is a natural ligand of ar...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neuroinflammation
Prif Awduron: Khan, Amir Saeed, Langmann, Thomas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7640677/
https://ncbi.nlm.nih.gov/pubmed/33143743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01999-8
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