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Engineering yeast for producing human glycoproteins: where are we now?

Yeast has advanced as an alternative for mammalian cell culture for the production of recombinant therapeutic glycoproteins. Engineered yeast strains not only allow to mimic the human N-glycosylation pathway but also specific types of human O-glycosylation. This is of great value for therapeutic pro...

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Pubblicato in:Future Microbiol
Autori principali: Laukens, Bram, De Visscher, Charlotte, Callewaert, Nico
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7617146/
https://ncbi.nlm.nih.gov/pubmed/25598335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fmb.14.104
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