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Engineering yeast for producing human glycoproteins: where are we now?

Yeast has advanced as an alternative for mammalian cell culture for the production of recombinant therapeutic glycoproteins. Engineered yeast strains not only allow to mimic the human N-glycosylation pathway but also specific types of human O-glycosylation. This is of great value for therapeutic pro...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Future Microbiol
Prif Awduron: Laukens, Bram, De Visscher, Charlotte, Callewaert, Nico
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7617146/
https://ncbi.nlm.nih.gov/pubmed/25598335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fmb.14.104
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