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Engineering yeast for producing human glycoproteins: where are we now?

Yeast has advanced as an alternative for mammalian cell culture for the production of recombinant therapeutic glycoproteins. Engineered yeast strains not only allow to mimic the human N-glycosylation pathway but also specific types of human O-glycosylation. This is of great value for therapeutic pro...

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Detalhes bibliográficos
Publicado no:Future Microbiol
Main Authors: Laukens, Bram, De Visscher, Charlotte, Callewaert, Nico
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7617146/
https://ncbi.nlm.nih.gov/pubmed/25598335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fmb.14.104
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