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NMR and EPR reveal a compaction of the RNA-binding protein FUS upon droplet formation
Many RNA-binding proteins undergo liquid-liquid phase separation, which underlies the formation of membrane-less organelles, such as stress granules and P-bodies. Studies of the molecular mechanism of phase separation in vitro is hampered by coalescence and sedimentation of organelle-sized droplets...
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| Publicado no: | Nat Chem Biol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7617049/ https://ncbi.nlm.nih.gov/pubmed/33686294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-021-00752-3 |
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