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Benefits and Challenges of Rare Genetic Variation in Alzheimer’s Disease

PURPOSE OF REVIEW: It is well established that sporadic Alzheimer’s disease (AD) is polygenic with common and rare genetic variation alongside environmental factors contributing to disease. Here, we review our current understanding of the genetic architecture of disease, paying specific attention to...

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Bibliografiske detaljer
Udgivet i:Curr Genet Med Rep
Main Authors: Grozeva, Detelina, Saad, Salha, Menzies, Georgina E., Sims, Rebecca
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7617023/
https://ncbi.nlm.nih.gov/pubmed/39649954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40142-019-0161-5
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