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Benefits and Challenges of Rare Genetic Variation in Alzheimer’s Disease

PURPOSE OF REVIEW: It is well established that sporadic Alzheimer’s disease (AD) is polygenic with common and rare genetic variation alongside environmental factors contributing to disease. Here, we review our current understanding of the genetic architecture of disease, paying specific attention to...

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Dades bibliogràfiques
Publicat a:Curr Genet Med Rep
Autors principals: Grozeva, Detelina, Saad, Salha, Menzies, Georgina E., Sims, Rebecca
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7617023/
https://ncbi.nlm.nih.gov/pubmed/39649954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40142-019-0161-5
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