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Nanozyme-catalysed CRISPR assay for preamplification-free detection of non-coding RNAs
CRISPR-based diagnostics enable specific sensing of DNA and RNA biomarkers associated with human diseases. This is achieved through the binding of guide RNAs to a complementary sequence which activates Cas enzymes to cleave reporter molecules. Currently, most CRISPR-based diagnostics rely on target...
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| Publicado no: | Nat Nanotechnol |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2022
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7616987/ https://ncbi.nlm.nih.gov/pubmed/35927321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41565-022-01179-0 |
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