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Extending the small-molecule similarity principle to all levels of biology with the Chemical Checker

Small molecules are usually compared by their chemical structure, but there is no unified analytic framework for representing and comparing their biological activity. We present the Chemical Checker (CC), which provides processed, harmonized and integrated bioactivity data on ~800,000 small molecule...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Biotechnol
Egile Nagusiak: Duran-Frigola, Miquel, Pauls, Eduardo, Guitart-Pla, Oriol, Bertoni, Martino, Alcalde, Víctor, Amat, David, Juan-Blanco, Teresa, Aloy, Patrick
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616951/
https://ncbi.nlm.nih.gov/pubmed/32440005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-020-0502-7
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