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Extending the small-molecule similarity principle to all levels of biology with the Chemical Checker

Small molecules are usually compared by their chemical structure, but there is no unified analytic framework for representing and comparing their biological activity. We present the Chemical Checker (CC), which provides processed, harmonized and integrated bioactivity data on ~800,000 small molecule...

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Dades bibliogràfiques
Publicat a:Nat Biotechnol
Autors principals: Duran-Frigola, Miquel, Pauls, Eduardo, Guitart-Pla, Oriol, Bertoni, Martino, Alcalde, Víctor, Amat, David, Juan-Blanco, Teresa, Aloy, Patrick
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616951/
https://ncbi.nlm.nih.gov/pubmed/32440005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-020-0502-7
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