An integrated taxonomy for monogenic inflammatory bowel disease

Complex diseases can have monogenic and polygenic forms that may inform on independent as well as converging mechanisms. Monogenic forms of inflammatory bowel disease (IBD) are caused by genetic defects that disrupt essential networks of intestinal homeostasis. Here, we use a quantitative framework...

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發表在:Gastroenterology
Main Authors: Bolton, Chrissy, Smillie, Christopher S., Elmentaite, Rasa, Wei, Gabrielle, Argmann, Carmen, Aschenbrenner, Dominik, James, Kylie R, McGovern, Dermot P.B, Macchi, Marina, Cho, Judy, Shouval, Dror, Kammermeier, Jochen, Koletzko, Sibylle, Peters, Lauren, Travis, Simon P.L., Jostins, Luke, Anderson, Carl A., Snapper, Scott, Klein, Christoph, Schadt, Eric, Zilbauer, Matthias, Xavier, Ramnik, Teichmann, Sarah, Muise, Aleixo M., Regev, Aviv, Uhlig, Holm H.
格式: Artigo
語言:Inglês
出版: 2022
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616885/
https://ncbi.nlm.nih.gov/pubmed/34780721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2021.11.014
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