An integrated taxonomy for monogenic inflammatory bowel disease

Complex diseases can have monogenic and polygenic forms that may inform on independent as well as converging mechanisms. Monogenic forms of inflammatory bowel disease (IBD) are caused by genetic defects that disrupt essential networks of intestinal homeostasis. Here, we use a quantitative framework...

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Vydáno v:Gastroenterology
Hlavní autoři: Bolton, Chrissy, Smillie, Christopher S., Elmentaite, Rasa, Wei, Gabrielle, Argmann, Carmen, Aschenbrenner, Dominik, James, Kylie R, McGovern, Dermot P.B, Macchi, Marina, Cho, Judy, Shouval, Dror, Kammermeier, Jochen, Koletzko, Sibylle, Peters, Lauren, Travis, Simon P.L., Jostins, Luke, Anderson, Carl A., Snapper, Scott, Klein, Christoph, Schadt, Eric, Zilbauer, Matthias, Xavier, Ramnik, Teichmann, Sarah, Muise, Aleixo M., Regev, Aviv, Uhlig, Holm H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2022
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616885/
https://ncbi.nlm.nih.gov/pubmed/34780721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2021.11.014
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