An integrated taxonomy for monogenic inflammatory bowel disease

Complex diseases can have monogenic and polygenic forms that may inform on independent as well as converging mechanisms. Monogenic forms of inflammatory bowel disease (IBD) are caused by genetic defects that disrupt essential networks of intestinal homeostasis. Here, we use a quantitative framework...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Gastroenterology
Prif Awduron: Bolton, Chrissy, Smillie, Christopher S., Elmentaite, Rasa, Wei, Gabrielle, Argmann, Carmen, Aschenbrenner, Dominik, James, Kylie R, McGovern, Dermot P.B, Macchi, Marina, Cho, Judy, Shouval, Dror, Kammermeier, Jochen, Koletzko, Sibylle, Peters, Lauren, Travis, Simon P.L., Jostins, Luke, Anderson, Carl A., Snapper, Scott, Klein, Christoph, Schadt, Eric, Zilbauer, Matthias, Xavier, Ramnik, Teichmann, Sarah, Muise, Aleixo M., Regev, Aviv, Uhlig, Holm H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2022
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616885/
https://ncbi.nlm.nih.gov/pubmed/34780721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2021.11.014
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