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Guide-independent DNA cleavage by archaeal Argonaute from Methanocaldococcus jannaschii
Prokaryotic Argonaute proteins acquire guide strands derived from invading or mobile genetic elements via an unknown pathway to direct guide-dependent cleavage of foreign DNA. Here, we report that Argonaute from the archaeal organism Methanocaldococcus jannaschii (MjAgo) possesses two modes of actio...
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| Publié dans: | Nat Microbiol |
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| Auteurs principaux: | , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7616673/ https://ncbi.nlm.nih.gov/pubmed/28319081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2017.34 |
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