COQ4 is required for the oxidative decarboxylation of the C1 carbon of Coenzyme Q in eukaryotic cells

Coenzyme Q (CoQ) is a redox lipid that fulfills critical functions in cellular bioenergetics and homeostasis. CoQ is synthesized by a multi-step pathway that involves several COQ proteins. Two steps of the eukaryotic pathway, the decarboxylation and hydroxylation of position C1, have remained unchar...

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Pubblicato in:Mol Cell
Autori principali: Pelosi, Ludovic, Morbiato, Laura, Burgardt, Arthur, Tonello, Fiorella, Bartlett, Abigail K., Guerra, Rachel M., Ferizhendi, Katayoun Kazemzadeh, Desbats, Maria Andrea, Rascalou, Bérengère, Marchi, Marco, Vázquez-Fonseca, Luis, Agosto, Caterina, Zanotti, Giuseppe, Roger-Margueritat, Morgane, Alcázar-Fabra, María, García-Corzo, Laura, Sánchez-Cuesta, Ana, Navas, Plácido, Brea-Calvo, Gloria, Trevisson, Eva, Wendisch, Volker F., Pagliarini, David J., Salviati, Leonardo, Pierrel, Fabien
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2024
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616408/
https://ncbi.nlm.nih.gov/pubmed/38295803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2024.01.003
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