Mutation of the ALS-/FTD-Associated RNA-Binding Protein FUS Affects Axonal Development

Aberrant condensation and localization of the RNA-binding protein (RBP) fused in sarcoma (FUS) occur in variants of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Changes in RBP function are commonly associated with changes in axonal cytoskeletal organization and branching in...

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Pubblicato in:J Neurosci
Autori principali: van Tartwijk, Francesca W., Wunderlich, Lucia C. S., Mela, Ioanna, Makarchuk, Stanislaw, Jakobs, Maximilian A. H., Qamar, Seema, Franze, Kristian, Kaminski Schierle, Gabriele S., St George-Hyslop, Peter H., Lin, Julie Qiaojin, Holt, Christine E., Kaminski, Clemens F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2024
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7616130/
https://ncbi.nlm.nih.gov/pubmed/38692734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2148-23.2024
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