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Regulation of BCR-mediated Ca2+ mobilization by MIZ1-TMBIM4 safeguards IgG1+ GC B cell-positive selection
The heavy chain isotype class confers specific properties to the antibody with critical consequences in infection and vaccination. For a robust class-switched antibody response, IgG1(+) B cells outcompete IgM(+) ones in germinal centers (GCs). Despite this knowledge the molecular mechanisms permitti...
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| Publicat a: | Sci Immunol |
|---|---|
| Autors principals: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2024
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7615907/ https://ncbi.nlm.nih.gov/pubmed/38579014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.adk0092 |
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