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Incorporating biological and clinical insights into variant choice for Mendelian randomisation: examples and principles

Mendelian randomisation is an accessible and valuable epidemiological approach to provide insight into the causal nature of relationships between risk factor exposures and disease outcomes. However, if performed without critical thought, we may simply have replaced one set of implausible assumptions...

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Detalhes bibliográficos
Publicado no:eGastroenterology
Main Authors: Burgess, Stephen, Cronjé, Héléne Toinét
Formato: Artigo
Idioma:Inglês
Publicado em: 2024
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615644/
https://ncbi.nlm.nih.gov/pubmed/38362310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/egastro-2023-100042
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