Mendelian Randomization Applied to Neurology: Promises and Challenges

The Mendelian randomization (MR) paradigm allows for causal inferences to be drawn using genetic data. In recent years, the expansion of well-powered publicly available genetic association data related to phenotypes such as brain tissue gene expression, brain imaging, and neurologic diseases offers...

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Vydáno v:Neurology
Hlavní autoři: Gagnon, Eloi, Daghlas, Iyas, Zagkos, Loukas, Sargurupremraj, Muralidharan, Georgakis, Marios K., Anderson, Christopher D., Cronje, Helene T., Burgess, Stephen, Arsenault, Benoit J., Gill, Dipender
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2024
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615637/
https://ncbi.nlm.nih.gov/pubmed/38261980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000209128
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