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Intrafemoral Injection of Human Hematopoietic Stem and Progenitor Cells into Immunocompromised Mice

Hematopoietic stem cells (HSCs) are defined by their lifelong ability to produce all blood cell types. This is operationally tested by transplanting cell populations containing HSCs into syngeneic or immunocompromised mice. The size and multilineage composition of the graft is then measured over tim...

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Bibliographische Detailangaben
Veröffentlicht in:J Vis Exp
Hauptverfasser: Calderbank, Emily F., Magnani, Laura, Laurenti, Elisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2023
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615601/
https://ncbi.nlm.nih.gov/pubmed/38145377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/66315
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