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Conditional inference in cis‐Mendelian randomization using weak genetic factors

Mendelian randomization (MR) is a widely used method to estimate the causal effect of an exposure on an outcome by using genetic variants as instrumental variables. MR analyses that use variants from only a single genetic region (cis‐MR) encoding the protein target of a drug are able to provide supp...

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Bibliographic Details
Published in:Biometrics
Main Authors: Patel, Ashish, Gill, Dipender, Newcombe, Paul, Burgess, Stephen
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2023
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615409/
https://ncbi.nlm.nih.gov/pubmed/37337418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.13888
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