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Emergence of ATP- and GTP-Binding Aptamers from Single RNA Sequences by Error-Prone Replication and Selection**

The spontaneous emergence of function from diverse RNA sequence pools is widely considered an important transition in the origin of life. Here we show that diverse sequence pools are not a prerequisite for the emergence of function. Starting five independent selection experiments each from a single...

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Pubblicato in:ChemSystemsChem
Autori principali: Wachowius, Falk, Porebski, Benjamin T., Johnson, Christopher M., Holliger, Philipp
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2023
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615363/
https://ncbi.nlm.nih.gov/pubmed/38074198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syst.202300006
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