Appraising the Causal Role of Risk Factors in Coronary Artery Disease and Stroke: A Systematic Review of Mendelian Randomization Studies

BACKGROUND: Mendelian randomization (MR) offers a powerful approach to study potential causal associations between exposures and health outcomes by using genetic variants associated with an exposure as instrumental variables. In this systematic review, we aimed to summarize previous MR studies and t...

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Vydáno v:J Am Heart Assoc
Hlavní autoři: Georgiou, Andrea N., Zagkos, Loukas, Markozannes, Georgios, Chalitsios, Christos V., Asimakopoulos, Alexandros G., Xu, Wei, Wang, Lijuan, Mesa‐Eguiagaray, Ines, Zhou, Xuan, Loizidou, Eleni M., Kretsavos, Nikolaos, Theodoratou, Evropi, Gill, Dipender, Burgess, Stephen, Evangelou, Evangelos, Tsilidis, Konstantinos K., Tzoulaki, Ioanna
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2023
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615320/
https://ncbi.nlm.nih.gov/pubmed/37804188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.122.029040
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