Appraising the Causal Role of Risk Factors in Coronary Artery Disease and Stroke: A Systematic Review of Mendelian Randomization Studies

BACKGROUND: Mendelian randomization (MR) offers a powerful approach to study potential causal associations between exposures and health outcomes by using genetic variants associated with an exposure as instrumental variables. In this systematic review, we aimed to summarize previous MR studies and t...

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Veröffentlicht in:J Am Heart Assoc
Hauptverfasser: Georgiou, Andrea N., Zagkos, Loukas, Markozannes, Georgios, Chalitsios, Christos V., Asimakopoulos, Alexandros G., Xu, Wei, Wang, Lijuan, Mesa‐Eguiagaray, Ines, Zhou, Xuan, Loizidou, Eleni M., Kretsavos, Nikolaos, Theodoratou, Evropi, Gill, Dipender, Burgess, Stephen, Evangelou, Evangelos, Tsilidis, Konstantinos K., Tzoulaki, Ioanna
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2023
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615320/
https://ncbi.nlm.nih.gov/pubmed/37804188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.122.029040
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