Appraising the Causal Role of Risk Factors in Coronary Artery Disease and Stroke: A Systematic Review of Mendelian Randomization Studies

BACKGROUND: Mendelian randomization (MR) offers a powerful approach to study potential causal associations between exposures and health outcomes by using genetic variants associated with an exposure as instrumental variables. In this systematic review, we aimed to summarize previous MR studies and t...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Georgiou, Andrea N., Zagkos, Loukas, Markozannes, Georgios, Chalitsios, Christos V., Asimakopoulos, Alexandros G., Xu, Wei, Wang, Lijuan, Mesa‐Eguiagaray, Ines, Zhou, Xuan, Loizidou, Eleni M., Kretsavos, Nikolaos, Theodoratou, Evropi, Gill, Dipender, Burgess, Stephen, Evangelou, Evangelos, Tsilidis, Konstantinos K., Tzoulaki, Ioanna
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2023
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615320/
https://ncbi.nlm.nih.gov/pubmed/37804188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.122.029040
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