Variant PNLDC1, Defective piRNA Processing and Azoospermia

BACKGROUND: P-element–induced wimpy testis (PIWI)–interacting RNAs (piRNAs) are short (21 to 35 nucleotides in length) and noncoding and are found almost exclusively in germ cells, where they regulate aberrant expression of transposable elements and postmeiotic gene expression. Critical to the proce...

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Bibliografski detalji
Izdano u:N Engl J Med
Glavni autori: Nagirnaja, Liina, Mørup, Nina, Nielsen, John E., Stakaitis, Rytis, Golubickaite, leva, Oud, Manon S., Winge, Sofia B., Carvalho, Filipa, Aston, Kenneth I., Khani, Francesca, van der Heijden, Godfried W., Marques, C. Joana, Skakkebaek, Niels E., Meyts, Ewa Rajpert-De, Schlegel, Peter N., Jørgensen, Niels, Veltman, Joris A., Lopes, Alexandra M., Conrad, Donald F., Almstrup, Kristian
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615015/
https://ncbi.nlm.nih.gov/pubmed/34347949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa2028973
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