The chaperone-binding activity of the mitochondrial surface receptor Tom70 protects the cytosol against mitoprotein-induced stress

Most mitochondrial proteins are synthesized as precursors in the cytosol and post-translationally transported into mitochondria. The mitochondrial surface protein Tom70 acts at the interface of the cytosol and mitochondria. In vitro import experiments identified Tom70 as targeting receptor, particul...

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Publicado no:Cell Rep
Main Authors: Backes, Sandra, Bykov, Yury S., Flohr, Tamara, Räschle, Markus, Zhou, Jialin, Lenhard, Svenja, Krämer, Lena, Mühlhaus, Timo, Bibi, Chen, Jann, Cosimo, Smith, Justin D., Steinmetz, Lars M., Rapaport, Doron, Storchová, Zuzana, Schuldiner, Maya, Boos, Felix, Herrmann, Johannes M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615001/
https://ncbi.nlm.nih.gov/pubmed/33826901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108936
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