The chaperone-binding activity of the mitochondrial surface receptor Tom70 protects the cytosol against mitoprotein-induced stress

Most mitochondrial proteins are synthesized as precursors in the cytosol and post-translationally transported into mitochondria. The mitochondrial surface protein Tom70 acts at the interface of the cytosol and mitochondria. In vitro import experiments identified Tom70 as targeting receptor, particul...

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Publicat a:Cell Rep
Autors principals: Backes, Sandra, Bykov, Yury S., Flohr, Tamara, Räschle, Markus, Zhou, Jialin, Lenhard, Svenja, Krämer, Lena, Mühlhaus, Timo, Bibi, Chen, Jann, Cosimo, Smith, Justin D., Steinmetz, Lars M., Rapaport, Doron, Storchová, Zuzana, Schuldiner, Maya, Boos, Felix, Herrmann, Johannes M.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615001/
https://ncbi.nlm.nih.gov/pubmed/33826901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108936
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