Ifu5, a WW domain-containing protein interacts with Efg1 to achieve coordination of normoxic and hypoxic functions to influence pathogenicity traits in Candida albicans

Hypoxic adaptation pathways, essential for Candida albicans pathogenesis, are tied to its transition from a commensal to a pathogen. Herein, we identify a WW domaincontaining protein, Ifu5, as a determinant of hypoxic adaptation that also impacts normoxic responses in this fungus. Ifu5 activity supp...

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Detalhes bibliográficos
Publicado no:Cell Microbiol
Main Authors: Rastogi, Sumit K., van Wijlick, Lasse, Ror, Shivani, Lee, Keunsook K., Román, Elvira, Agarwal, Pranjali, Manzoor, Nikhat, Gow, Neil A.R., Pla, Jesús, Ernst, Joachim F., Panwar, Sneh L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614792/
https://ncbi.nlm.nih.gov/pubmed/31736226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.13140
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