The angiopoietin receptor Tie2 is atheroprotective in arterial endothelium

Leukocytes and resident cells in the arterial wall contribute to atherosclerosis, especially at sites of disturbed blood flow. Expression of endothelial Tie1 receptor tyrosine kinase is enhanced at these sites, and attenuation of its expression reduces atherosclerotic burden and decreases inflammati...

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Pubblicato in:Nat Cardiovasc Res
Autori principali: Anisimov, Andrey, Fang, Shentong, Hemanthakumar, Karthik Amudhala, Örd, Tiit, van Avondt, Kristof, Chevre, Raphael, Toropainen, Anu, Singha, Prosanta, Gilani, Huda, Nguyen, Su D., Karaman, Sinem, Korhonen, Emilia A., Adams, Ralf H., Augustin, Hellmut G., Öörni, Katariina, Soehnlein, Oliver, Kaikkonen, Minna U., Alitalo, Kari
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2023
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614785/
https://ncbi.nlm.nih.gov/pubmed/37476204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s44161-023-00224-y
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