Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor

Homologous recombination is a fundamental process of life. It is required for the protection and restart of broken replication forks, the repair of chromosome breaks, and the exchange of genetic material during meiosis. Individuals with mutations in key recombination genes, such as BRCA2 (FANCD1), o...

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Udgivet i:Nature
Main Authors: Greenhough, Luke A., Liang, Chih-Chao, Belan, Ondrej, Kunzelmann, Simone, Maslen, Sarah, Rodrigo-Brenni, Monica C., Anand, Roopesh, Skehel, Mark, Boulton, Simon J., West, Stephen C.
Format: Artigo
Sprog:Inglês
Udgivet: 2023
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614784/
https://ncbi.nlm.nih.gov/pubmed/37344587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-023-06179-1
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