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Acetylcholine boosts dendritic NMDA spikes in a CA3 pyramidal neuron model
Acetylcholine has been proposed to facilitate the formation of memory ensembles within the hippocampal CA3 network, by enhancing plasticity at CA3-CA3 recurrent synapses. Regenerative NMDA receptor (NMDAR) activation in CA3 neuron dendrites (NMDA spikes) increase synaptic Ca(2+) influx and can trigg...
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| Publicado no: | Neuroscience |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2022
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614718/ https://ncbi.nlm.nih.gov/pubmed/34780920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2021.11.014 |
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