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Dendritic NMDA spikes are necessary for timing-dependent associative LTP in CA3 pyramidal cells

The computational repertoire of neurons is enhanced by regenerative electrical signals initiated in dendrites. These events, referred to as dendritic spikes, can act as cell-intrinsic amplifiers of synaptic input. Among these signals, dendritic NMDA spikes are of interest in light of their correlati...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Brandalise, Federico, Carta, Stefano, Helmchen, Fritjof, Lisman, John, Gerber, Urs
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116082/
https://ncbi.nlm.nih.gov/pubmed/27848967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13480
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