Mendelian randomization

Mendelian randomization (MR) is a term that applies to the use of genetic variation to address causal questions about how modifiable exposures influence different outcomes. The principles of MR are based on Mendel’s laws of inheritance and instrumental variable estimation methods, which enable the i...

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Bibliografiske detaljer
Udgivet i:Nat Rev Methods Primers
Main Authors: Sanderson, Eleanor, Glymour, M. Maria, Holmes, Michael V., Kang, Hyunseung, Morrison, Jean, Munafò, Marcus R., Palmer, Tom, Schooling, C. Mary, Wallace, Chris, Zhao, Qingyuan, Smith, George Davey
Format: Artigo
Sprog:Inglês
Udgivet: 2022
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614635/
https://ncbi.nlm.nih.gov/pubmed/37325194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s43586-021-00092-5
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