Dephosphorylation of the proneural transcription factor ASCL1 re-engages a latent post-mitotic differentiation programme in neuroblastoma

Paediatric cancers often resemble trapped developmental intermediate states that fail to engage the normal differentiation programme, typified by high-risk neuroblastoma arising from the developing sympathetic nervous system. Neuroblastoma cells resemble arrested neuroblasts trapped by a stable but...

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Bibliografiske detaljer
Udgivet i:Mol Cancer Res
Main Authors: Ali, Fahad R., Marcos, Daniel, Chernukhin, Igor, Woods, Laura M., Parkinson, Lydia M., Wylie, Luke A., Papkovskaia, Tatiana D., Davies, John D., Carroll, Jason S., Philpott, Anna
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614603/
https://ncbi.nlm.nih.gov/pubmed/33046535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-20-0693
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