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Emerging mechanisms of telomerase reactivation in cancer
Mutations in the promoter of human telomerase reverse transcriptase (hTERT) result in hyperactivation of hTERT. Notably, all mutations are G>A transitions, frequently found in a wide range of cancer types, and causally associated with cancer progression. Initially, the mutations were understood t...
Shranjeno v:
| izdano v: | Trends Cancer |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2022
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614490/ https://ncbi.nlm.nih.gov/pubmed/35568649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2022.03.005 |
| Oznake: |
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