Abnormal folate metabolism in fetuses affected by neural tube defects

Folic acid supplementation can prevent many cases of neural tube defects (NTDs) whereas sub-optimal maternal folate status is a risk factor, suggesting that folate metabolism is a key determinant of susceptibility to NTDs. Despite extensive genetic analysis of folate cycle enzymes, and quantificatio...

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Veröffentlicht in:Brain
Hauptverfasser: Dunlevy, Louisa P.E., Chitty, Lyn S., Burren, Katie A., Doudney, Kit, Stojilkovic-Mikic, Taita, Stanier, Philip, Scott, Rosemary, Copp, Andrew J., Greene, Nicholas D.E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614420/
https://ncbi.nlm.nih.gov/pubmed/17438019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awm028
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