Frequent use of IGHV3-30-3 in SARS-CoV-2 neutralizing antibody responses

The antibody response to SARS-CoV-2 shows biased immunoglobulin heavy chain variable (IGHV) gene usage, allowing definition of genetic signatures for some classes of neutralizing antibodies. We investigated IGHV gene usage frequencies by sorting spike-specific single memory B cells from individuals...

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Publicado en:Front Virol
Main Authors: Pushparaj, Pradeepa, Nicoletto, Andrea, Castro Dopico, Xaquin, Sheward, Daniel J., Kim, Sungyong, Ekström, Simon, Murrell, Ben, Corcoran, Martin, Karlsson Hedestam, Gunilla B.
Formato: Artigo
Idioma:Inglês
Publicado: 2023
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614418/
https://ncbi.nlm.nih.gov/pubmed/37041983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fviro.2023.1128253
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