Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy

BACKGROUND: Cellular insulin resistance is the hallmark of type 2 diabetes and predominantly affects adipose and muscle cells. The saturated free fatty acid palmitate is elevated in insulin-resistant states and may directly contribute to cellular insulin resistance. A spectrum of renal disease is as...

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Опубликовано в: :Nephrol Dial Transplant
Главные авторы: Lennon, Rachel, Pons, Deborah, Sabin, Matthew A, Wei, Christina, Shield, Julian P, Coward, Richard J, Tavaré, Jeremy M, Mathieson, Peter W, Saleem, Moin A, Welsh, Gavin I
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614380/
https://ncbi.nlm.nih.gov/pubmed/19556298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfp302
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