TSHZ2 is an EGF-regulated tumor suppressor that binds to the cytokinesis regulator PRC1 and inhibits metastasis

Unlike early transcriptional responses to mitogens, later events are less well-characterized. Here, we identified delayed down-regulated genes (DDGs) in mammary cells after prolonged treatment with epidermal growth factor (EGF). The expression of these DDGs was low in mammary tumors and correlated w...

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Udgivet i:Sci Signal
Main Authors: Uribe, Mary L., Dahlhoff, Maik, Batra, Rajbir N., Nataraj, Nishanth B., Haga, Yuya, Drago-Garcia, Diana, Marrocco, Ilaria, Sekar, Arunachalam, Ghosh, Soma, Vaknin, Itay, Lebon, Sacha, Kramarski, Lior, Tsutsumi, Yasuo, Choi, Inpyo, Rueda, Oscar M., Caldas, Carlos, Yarden, Yosef
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614343/
https://ncbi.nlm.nih.gov/pubmed/34158398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.abe6156
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