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RNA therapeutics for improving CAR T cell safety and efficacy

Autologous chimeric antigen receptor (CAR) T cells have recently emerged as potent tools in the fight against cancer, with promising therapeutic efficacy against haematological malignancies. However, several limitations hamper their widespread clinical use, including availability of target antigen,...

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Detalles Bibliográficos
Publicado en:Cancer Res
Main Authors: Schaible, Philipp, Bethge, Wolfgang, Lengerke, Claudia, Haraszti, Reka Agnes
Formato: Artigo
Idioma:Inglês
Publicado: 2023
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614194/
https://ncbi.nlm.nih.gov/pubmed/36512627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-22-2155
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