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Development of CAR T cells designed to improve antitumor efficacy and safety
Chimeric antigen receptor (CAR) T cell therapy has shown promising efficacy against hematologic malignancies. Antitumor activity of CAR T cells, however, needs to be improved to increase therapeutic efficacy in both hematologic and solid cancers. Limitations to overcome are ‘on-target, off-tumor’ to...
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| Publicado no: | Pharmacol Ther |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5601024/ https://ncbi.nlm.nih.gov/pubmed/28342824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2017.03.012 |
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