Ipecac root extracts and isolated circular peptides differentially suppress inflammatory immune response characterised by proliferation, activation and degranulation capacity of human lymphocytes in vitro

Circular peptides are attractive lead compounds for drug development; this study investigates the immunomodulatory effects of defined root powder extracts and isolated peptides (called cyclotides) from Carapichea ipecacuanha (Brot.) L. Andersson (‘ipecac’). Changes in the viability, proliferation an...

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Bibliografski detalji
Izdano u:Biomed Pharmacother
Glavni autori: Falanga, Chiara Madlen, Steinborn, Carmen, Muratspahić, Edin, Zimmermann-Klemd, Amy Marisa, Winker, Moritz, Krenn, Liselotte, Huber, Roman, Gruber, Christian W., Gründemann, Carsten
Format: Artigo
Jezik:Inglês
Izdano: 2022
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614192/
https://ncbi.nlm.nih.gov/pubmed/35653889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopha.2022.113120
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