Ipecac root extracts and isolated circular peptides differentially suppress inflammatory immune response characterised by proliferation, activation and degranulation capacity of human lymphocytes in vitro

Circular peptides are attractive lead compounds for drug development; this study investigates the immunomodulatory effects of defined root powder extracts and isolated peptides (called cyclotides) from Carapichea ipecacuanha (Brot.) L. Andersson (‘ipecac’). Changes in the viability, proliferation an...

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Detalhes bibliográficos
Publicado no:Biomed Pharmacother
Main Authors: Falanga, Chiara Madlen, Steinborn, Carmen, Muratspahić, Edin, Zimmermann-Klemd, Amy Marisa, Winker, Moritz, Krenn, Liselotte, Huber, Roman, Gruber, Christian W., Gründemann, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614192/
https://ncbi.nlm.nih.gov/pubmed/35653889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopha.2022.113120
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