Mechanical stress driven by rigidity sensing governs epithelial stability

Epithelia act as a barrier against environmental stress and abrasion and in vivo they are continuously exposed to environments of various mechanical properties. The impact of this environment on epithelial integrity remains elusive. By culturing epithelial cells on 2D hydrogels, we observe a loss of...

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Detalhes bibliográficos
Publicado no:Nat Phys
Main Authors: Sonam, Surabhi, Balasubramaniam, Lakshmi, Lin, Shao-Zhen, Ivan, Ying Ming Yow, Jaumà, Irina Pi, Jebane, Cecile, Karnat, Marc, Toyama, Yusuke, Marcq, Philippe, Prost, Jacques, Mège, René-Marc, Rupprecht, Jean-François, Ladoux, Benoît
Formato: Artigo
Idioma:Inglês
Publicado em: 2023
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614076/
https://ncbi.nlm.nih.gov/pubmed/36686215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41567-022-01826-2
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