Mucin O-glycans are natural inhibitors of Candida albicans pathogenicity

Mucins are large gel-forming polymers inside the mucus barrier that inhibit the yeast to hyphal transition of Candida albicans, a key virulence trait of this important human fungal pathogen. However, the molecular motifs in mucins that inhibit filamentation remain unclear, despite their potential fo...

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Опубликовано в: :Nat Chem Biol
Главные авторы: Takagi, Julie, Aoki, Kazuhiro, Turner, Bradley S., Lamont, Sabrina, Lehoux, Sylvain, Kavanaugh, Nicole, Gulati, Megha, Arevalo, Ashley Valle, Lawrence, Travis J., Kim, Colin Y., Bakshi, Bhavya, Ishihara, Mayumi, Nobile, Clarissa J., Cummings, Richard D., Wozniak, Daniel, Tiemeyer, Michael, Hevey, Rachel, Ribbeck, Katharina
Формат: Artigo
Язык:Inglês
Опубликовано: 2022
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613833/
https://ncbi.nlm.nih.gov/pubmed/35668191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-022-01035-1
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